West Ham will be looking for a fourth Premier League win in a row when they travel to Fulham on Saturday (kick-off 5.30pm).
Manuel Pellegrini said West Ham should ignore their upcoming kind fixture list and focus on Tuesday's opponents Cardiff.
Manchester City's ruthless defence of their Premier League title takes them to east London to face on Saturday.
Huddersfield are chasing back-to-back wins for the first time since February as West Ham visit the John Smith's Stadium.
West Ham will still be without captain Mark Noble when Burnley visit the London Stadium on Saturday.
Mauricio Pochettino is planning to ring the changes for Tottenham's Carabao Cup fourth-round clash with West Ham on Wednesday, but says Christian Eriksen and Dele Alli may play.
Christian Eriksen and Mousa Dembele will be available for Tottenham as they take on West Ham in a Premier League London derby on Saturday.
Jose Izquierdo is set to feature for Brighton in their Friday Night Football clash against West Ham after recovering from a knee problem.
Marko Arnautovic will return to the West Ham team as Manchester United look to end a disastrous week on a positive note at the London Stadium.
West Ham manager Manuel Pellegrini will make changes for the visit of Macclesfield in the Carabao Cup.